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The University of Arizona 1993-95 General Catalog Catalog Home All UA Catalogs UA Home
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Molecular and Cellular Biology (MCB) Life Sciences South Building, Room 444 (520) 621-7560 Professors Samuel Ward, Head, H. Vasken Aposhian, Hans Bohnert (Biochemistry), Don Bourque (Biochemistry), George T. Bowden (Radiation Oncology), Robert P. Erickson (Pediatrics), Wayne R. Ferris (Emeritus), William J. Grimes (Biochemistry), Mac E. Hadley (Anatomy), Richard B. Hallick (Biochemistry), John Hildebrand (Arizona Research Laboratory), Henry Koffler (Biochemistry, Microbiology and Immunology), Brian Larkins (Plant Sciences), John Little (Biochemistry), Neil H. Mendelson, David W. Mount, Gene Myers (Computer Science), Nobuyoshi Shimizu, Paul Sypherd, Hans Van Etten (Plant Pathology) Associate Professors Danny Brower, Gail Burd (Anatomy), Carol Dieckmann (Biochemistry), Jennifer D. Hall, Martha Hawes (Plant Pathology), Martinez J. Hewlett, Thomas J. Lindell, Elizabeth Vierling (Biochemistry) Assistant Professors Alison Adams, Herman Gordon (Anatomy), Lynn Manseau, Roger L. Miesfeld (Biochemistry), Karen Oishi, Roy Parker, Mary Rykowski (Anatomy), Scott Selleck (Arizona Reseach Laboratories), Ted Weinert The University Department of Molecular and Cellular Biology offers the Bachelor of Science, Master of Science, and Doctor of Philosophy degrees with a major in molecular and cellular biology. The department will only admit graduate students whose stated objective is the Doctor of Philosophy degree. The major: 181R, 182, 320, 410, 411, 462a, and at least three units of an upper-division laboratory course (such as 413, 473 or 494); CHEM 103a-103b, 104a-104b, 241a-241b, 243a-243b; PHYS 104a- 104b; MATH 125a or 124 and 125b. Writing emphasis course requirements can be met by taking 404, 470, 473, 455 or 498H. With the assistance of a major advisor, the student must select a minimum of 30 units, including at least 6 units of upper-division molecular and cellular biology courses. All majors are encouraged to undertake independent research and they are strongly advised to include CHEM 480a-480b in their program. Biology teaching major: Students interested in teaching secondary school biology, which includes molecular and cellular biology, should see the list of required courses under Department of Ecology and Evolutionary Biology. The minor: The department has a structured split minor involving chemistry, physics, and mathematics. The department participates in the honors program. Core courses all have additional honors credit. 181L. Introductory Biology Laboratory (1) I Laboratory exercises presenting techniques and fundamental principles of modern biology. Designed to complement the information concurrently presented in 181R. P, 181R or CR, 181R. (Identical with BIOC 181L, ECOL 181L, MIC 181L) 181R. Introductory Biology I (3) I Introduction to the cell and its properties, basic genetics, the immune system, recombinant DNA technology with illustrations from bacteria, plants, animals and humans. High school biology/chemistry recommended. Honors section available for 4 units. P, CR 181L. (Identical with BIOC 181R, ECOL 181R, MIC 181R) 182. Introductory Biology II (4) II (Identical with ECOL 182) 195. Colloquium a. Great Experiments in Microbiology (1) I II (Identical with MIC 195a) b. Biotechnology (1) I II (Identical with BIOC 195a) c. Society and Science (1) I II (Identical with BIOC 195c, which is home) 320. Genetics (4) I (Identical with ECOL 320) 404. Contemporary Biology in Human Affairs (3) II Advances in biomedical research will be reviewed and their ethical, social and legal implications discussed. P, one course in BIOC or biology; botany not acceptable. 410. Cell Biology (3) II The molecular basis of the structure and function of animal, plant and prokaryotic cells with emphasis on experimental analysis. P, 181, 182, 462a, recommend 320 and CR 411. (Identical with BIOC 410 and MIC 410) Honors section available for (4) honors credits. 411. Molecular Biology (3) II Mechanisms of genome replication, genetic recombination, DNA repair, gene expression and regulation. P, 181, BIOC 462a. recommend 320 (Identical with BIOC 411 and MIC 411) May be convened with 511. Honors section available for (4) honors credits). 413. Somatic Cell and Molecular Genetics Laboratory (3) I Modern lab. techniques for genetic and molecular analyses of mammalian cells in culture. 6L. P, 181. May be convened with 513. 415. Somatic Cell and Molecular Genetics (2) II Modern concepts of eucaryotic cell genetics and molecular mechanisms of cell growth control. P, 181. (Identical with GENE 415) May be convened with 515. 416. Computer Analysis of Sequences (3) II Analysis of protein and DNA sequence information using computer methods. Consult instructor for appropriate prerequisites before enrolling (Identical with BIOC 416, ECOL 416 and GENE 416). May be convened with 516. 421a-421b. Microbiological Techniques (3-3) (Identical with MIC 421a-421b) 428. Microbial Genetics (3) II (Identical with PL P 428) 429. General Virology (3) II (Identical with MIC 429) 437. Vertebrate Physiology (4) I (Identical with ECOL 437) 443. Insect Neurobiology (3) II (Identical with ENTO 443) May be convened with 543. 455. Developmental Mechanisms (3) I Molecular and cellular mechanisms of development, with emphasis on model systems. P, 181 and an advanced course in genetics, molecular or cell biology. (Identical with BIOC 455) 456. Developmental Biology (3) I (Identical with ANAT 456) May be convened with 556. 457. Experiments in Developmental Biology (4) II (Identical with ANAT 457) May be convened with 557. 460. Plant Physiology (4) I (Identical with PL S 460) May be convened with 560. 461. Neurobiology (4) I Cellular, molecular, and development biology of nerve cells, synapses, and neural systems. (Identical with NRSC 461) P, 181, 182 or equivalents. 462a-462b. Biochemistry (3) II (Identical with BIOC 462a-462b) Honors section available for (4) honors credits. 466. Physiology Laboratory (3) II (Identical with ECOL 466) May be convened with 566. 467R. Endocrinology (3) II (Identical with ANAT 467R) May be convened with 567R. 469. Developmental Neurobiology (2) II Development of the nervous systems of invertebrates and vertebrates from embryonic stages to the adult. P, 8 units of biology. 470. The Cell and the Environment (3) I The molecular and cellular responses to the environment. P, MCB 410 and/or Biochemistry. 471. Human Embryology (4) II (Identical with ANAT 471) May be convened with 571. 473. Recombinant DNA Methods and Applications (4) II Relevant techniques for the isolation, purification and cloning of genes in E. Coli hosts. Eucaryotic lambda genomic DNA clones will be characterized by restriction mapping, hybridization analysis, and sequence analysis. 2R, 6L. P, BIOC 462a, CR 411. (Identical with BIOC 473, GENE 473, MIC 473, and PL S 473) 496. Seminar a. Developmental Biology (1) [Rpt./6] I II Consult instructor before enrolling. May be convened with 596a. b. Cell Biology (1) [Rpt./6] I II Consult instructor before enrolling. May be convened with 596b. d Molecular Genetics (1) [Rpt./6] I II Consult instructor before enrolling. May be convened with 596d. e Molecular Bioology (1) [Rpt./6] I II Consult instructor before enrolling. May be convened with 596e. 497. Workshop. Special Tutoring Workshop (1-3) [Rpt] I II Open to senior MCB and Biochemistry majors only. Consult department before enrolling. (Identical with BIOC 497a) 501. Molecular and Cellular Biology (4) I P, formal admission to the Ph.D./M.D. program and permission of the course director. 505. Eukaryotic DNA Replication (3) [Rpt./1] I 1994-95 (Identical with CBIO 505) 510. Plant Molecular Biology (3) II 1994-95 (Identical with BIOC 510) 511. Molecular Biology (3) II For a description of course topics, see 411. Graduate-level requirements include attending an additional lecture hour per week to discuss independent research, and to perform at a level 10% above undergraduate students. MCB majors should not take this course for graduate credit. P, 462a and consult department before enrolling. (Identical with BIOC 511 and MBIM 511) May be convened with 411. 513. Somatic Cell and Molecular Genetics Laboratory (3) I For a description of course topics, see 413. Graduate-level requirements include an oral presentation. P, 181. May be convened with 413. 515. Somatic Cell and Molecular Genetics (2) II For a description of course topics, see 415. Graduate-level requirements include reading papers from the current literature. P, 181. (Identical with GENE 515) May be convened with 415. 516. Computer Analysis of Sequences (3) II For description of course topics, see 416. Graduate students will be required to conduct a research project, submit a written report, and give a presentation in class. (Identical with BIOC 516, ECOL 516 and GENE 516). May be convened with 416. 520. Pathways and Signals in Cells (3) II (Identical with BIOC 520). 543. Insect Neurobiology (3) II (Identical with ENTO 543) May be convened with 443. 545. Concepts in Genetic Analysis (3) I Methods of genetic analysis including mutant isolation, genetic and physical mapping, reverse genetics, evolutionary mechanisms, molecular variation and genomic evolution. P, introductory undergraduate genetics course or biology course. (Identical with BIOC 545, ECOL 545, GENE 545) 550. Topics in Pigment Cell Biology (2) I (Identical with ANAT 550) 555. Molecular Mechanisms of Development (3) II Detailed examination of molecular, genetic and cellular approaches to selected problems in developmental biology. P, 545, 568 or consult department before enrolling. (Identical with BIOC 555 and GENE 555) 556. Developmental Biology (3) I (Identical with ANAT 556) May be convened with 456. 557. Experiments in Developmental Biology (4) II (Identical with ANAT 557) May be convened with 457. 558. Advanced Subjects in Endocrinology (2) [Rpt.] I (Identical with ANAT 558) 560. Plant Physiology (4) I (Identical with PL S 560) May be convened with 460. 562. Plant Intermediary Metabolism (3) II 1993-94 (Identical with PL S 562) 564. Plant Growth and Development (3) II 1993-94 (Identical with PL S 564) 566. Physiology Laboratory (3) II (Identical with ECOL 566) May be convened with 466. 567R. Endocrinology (3) II (Identical with ANAT 567R) May be convened with 467R. 568. Nucleic Acids (4) I (Identical with BIOC 568) 569. Topics in Gene Regulations (2) II 1994-95 (Identical with BIOC 569) 571. Human Embryology (4) II (Identical with ANAT 571) May be convened with 471. 572. Biological Regulation (4) I (Identical with BIOC 572). 574. Advances in Mammalian Genetics (2) [Rpt./1] I 1994-95 (Identical with BIOC 574) 575. Special Topics in Biological Imaging (2) (Identical with ANAT 575) 577. Principles of Cell Biology (4) II (Identical with ANAT 577) 582. Topics in Neural Development (2) II 1993-94 (Identical with NRSC 582) 583. Topics in Neural Plasticity (2) II 1993-94 Reading and discussion of primary literature on cellular, biochemical, physiological, and structural changes that occur on the adult nervous system. P, a course in neurobiology, consult department before enrolling. (Identical with ANAT 583 and NRSC 583) 584. Cellular Neurobiology (2) II 1993-94 (Identical with ANAT 584) 586. Intracellular Messengers (2) I 1993-94 (Identical with NRSC 586) 587. Biology of Neurological Disease (3) II 1993-94 (Identical with NRSC 587) 588. Principles of Cellular and Molecular Neurobiology (4) I (Identical with NRSC 588) 589. Cancer Genetics and Cytogenetics (3) I 1993-94 (Identical with CBIO 589) 595. Colloquium a. Topics in Molecular Biology (1) [Rpt./6] I II Open to majors only. d. Special Topics in Cell Biology (2) [Rpt./3] II (Identical with CBIO 595d, which is home) 596. Seminar a. Developmental Biology (1) [Rpt./6] I II Consult instructor before enrolling. May be convened with 496a. b. Cell Biology (1) [Rpt./6] I II Consult instructor before enrolling. May be convened with 496b. c. Concepts in Cellular Differentiation (2) I (Identical with ANAT 596c) d. Molecular Genetics (1) [Rpt./6] I II Consult instructor before enrolling. May be convened with 496d. e. Molecular Bioology (1) [Rpt./6] I II Consult instructor before enrolling. May be convened with 496e. 597. Workshop a. Recombinant DNA Techniques (2) S (Identical with BIOC 597a, which is home) 601. Molecular and Cellular Biology (4) I Acquire a basic understanding of modern genetics, molecular biology and cell biology, and learn how to apply that understanding to human disease. Open to students in the Masters degree program in Genetic Counseling only. (Identical with GENE 601). 612. Biological Electron Microscopy (4) I Provides theoretical background and practical experience in transmission and scanning electron microscopy that are necessary for the efficient and effective application of ultrastructural and cytochemical techniques as research tools. 2R, 6L. P, one college level course in each of physics, chemistry and biology (Identical with ANAT 612, AN S 612, BIOC 612, ENTO 612, MIC 612, PATH 612, PSIO 612, PL P 612, V SC 612) 621. Molecular, Plant, Microbe Interactions (3) I 1993-94 (Identical with PL P 621) 695. Colloquium a. Current Topics in Plant Biology (1) [Rpt./3] I II (Identical with PL P 695a, which is home) e. Science, Society and Ethics (1) II (Identical with GENE 695e and NRSC 695e) 696. Seminar a. Developmental Biology (1) [Rpt./6] I II To be taken only when 596a repeated course limit has been met. b. Cell Biology (1) [Rpt./6] I II P, 596b. To be taken only when 596b repeated course limit has been met. d. Molecular Genetics (1) [Rpt./6] I II P, 596d. To be taken only when 596d repeated course limit has been met. e. Molecular Bioology (1) [Rpt./6] I II P, 596e. To be taken only when 596e repeated course limit has been met. 697. Workshop a. Scientific Infrastructure (2) I II Open to majors only. 761. Laboratory Rotation I (2) [Rpt./1] I II Research project with graduate faculty for 8 weeks, 15 hours per week. Open to majors only. 762. Laboratory Rotation II (2) [Rpt./1] I II Research project with graduate faculty for 8 weeks, 15 hours per week. Open to majors only. 763. Laboratory Rotation III (2) I II Research project with graduate faculty for 8 weeks, 15 hours per week. Open to majors only. 801. Molecular and Cellular Biology (4) I Freshman medical students only. |
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