PCOL601A
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PCOL601A - Epigenetics in Development and Disease
Course ID
039271
Course Description
Epigenetics is the study of heritable changes in gene function that occur in the absence of changes in DNA sequence. Epigenetic mechanisms of gene control are important to orderly cell, tissue, and organismal development and the disruption of these mechanisms participates in the etiology of complex human disease. Topics include overview and concepts of epigenetics, histones and their modifications, DNA methylation, chromatin structure, RNAi, model organisms, nuclear transplantation and genome reprogramming, epigenetic and epigenomic technologies, and therapeutic agents that target epigenetic mechanisms.
Min Units
2
Max Units
2
Repeatable for Credit
Yes
Total Completions Allowed
2
Total Units Allowed
4
Grading Basis
GRD - Regular Grades A, B, C, D, E
Career
Graduate
Course Requisites
May be convened with
Component
Lecture
Optional Component
No