CMM695L

039736

An interactive graduate-level course focused on how inflammation and immune function/dysfunction contributes to key biological and medical aspects of aging. This course will evaluate the basic biology of aging with a focus on how the aging immune system impacts geriatric principles of care, common geriatric syndromes and aging-associated disease, the biologic basis of health disparities (where known), and other unique issues related to aging research. The course is open to both graduate students and medical students/residents. Graduate students funded through the Training Grant will be required to attend in their 3rd and 4th year in place of Journal Club. The course is comprised of three aspects: literature review, topic discussion, and attendance in the Advances in Aging Lecture Series (Grand Rounds). Students will be assigned relevant literature to review in advance of in-class discussion on topics in aging research. Each discussion will be led by an expert in the field. The Advances in Aging Lecture Series are 1-hour Grand Rounds that meet once per month and will add clinical perspective to the field of aging research. More information on Advances in Aging Lecture Series topics and archived lectures is available at http://aging.arizona.edu/program/advances-aging-lecture-series. Topics that will be covered in the course include: Introduction to Aging Research, Aging Theories, and Model Organisms; Replicative Senescence as a Driver of Age-Associated Inflammation; DNA Damage, Repair, and Oncogenesis; Mitochondrial Aging and Metabolism; Musculoskeletal Changes in Aging and Frailty; Infection and lmmunosenescence; Aging with HIV in the age of ART; Microbiota in Aging; Neural Changes, Neurodegeneration, and Alzheimer's Disease; Cardiovascular Aging and Stroke; Stem Cell Aging and Longevity Extension/Rejuvenation Research.

GRD - Regular Grades A, B, C, D, E

Graduate

CE - CL (Cross Listed), GIDP - CBIO (Cancer Biology), GIDP - PS (Physiological Sciences)