MCB295C

040081

25 years ago, Mike Hall and colleagues discovered a novel kinase they named the Target of Rapamycin (TOR or mTOR). This kinase is now known to act as the master regulator of cell growth and metabolism in eukaryotes. Accordingly, defects in TOR function underlie many diseases including cancer, clinical depression, and diabetes. In this class students will learn about modern research in molecular and systems biology by walking through the major discoveries in the TOR signaling field--starting with basic research in yeast and moving to the study of disease and aging in humans. Each class period will focus on a new discovery and the experimental method(s) that were used to make that discovery. Students will practice interpreting real experimental data during class sessions and read and summarize a new paper in the TOR field for their final project.

SPF - Alternative Grading S, P, F

Undergraduate

018112