PCOL488

042425

This course will integrate and consolidate the basic concepts of chemistry, biochemistry, and pharmacology that underlie drug discovery, design, and development. For selected drug classes, the course will lead students into a deeper understanding of pharmacodynamics beyond pharmacophore and target. Students will learn hands-on computational approaches that emphasize the 3-dimensional nature of drugs and their interaction with proteins to both explore and optimize these interactions. In a team science setting, students will identify a therapeutic target, design small molecules to engage the target and conceptualize the synthesis and testing of these molecules along the drug discovery pipeline, including the consideration of screening approaches, ADMET, and the competitive landscape. The course will use in-class work and a final team presentation of drug discovery projects in the form of a pitch to business and academic experts.

GRD - Regular Grades A, B, C, D, E

Undergraduate

018867